Propolis contains up to 10% essential oils, more in quantity than most aromatic plants. This could explain why each time we smell propolis or air from the beehive, we experience a nice, relaxing sensation...
TherapeuticEffects of Propolis Essential Oil on Anxiety of Restraint-Stressed Mice
Hum Exp Toxicol, 2012, February
Propolishas a broad spectrum of biological activities; however, whether its essentialoils have neuroprotective effects is unknown.
In thisstudy, we found that propolis essential oil (PEO) could significantly reverse theanxiety-like behavior of restraint-stressed mice, and has no effect onlocomotor activity. Furthermore, PEO significantly decreased the plasma levelsof cortisol (CORT), adrenocorticotropic hormone (ACTH) and malondialdehyde(MDA), whereas it increased the activity of superoxide dismutase (SOD) inrestraint-stressed mice.
Theseresults strongly suggest that PEO has therapeutic effects on anxiety throughantagonizing the hyperfunction of hypothalamic–pituitary–adrenal (HPA) axis andimproving the ability of antioxidation in brain tissue.
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