Showing posts with label gastric ulcers. Show all posts
Showing posts with label gastric ulcers. Show all posts

A Review of Honey and Microbial Infections

a peer-reviewed article from the Journal of Medicinal Food... did someone say medicine in a jar?


Honey and Microbial Infections: A Review Supporting the Use of Honey for Microbial Control
Noori S. Al-Waili, Khelod Salom, Glenn Butler and Ahmad A. Al Ghamdi. Journal of Medicinal Food, 22 Aug 2011



Honey has been used as a medicine throughout the ages and has recently been reintroduced to modern medical practice. Much of the research to date has addressed honey's antibacterial properties and its effects on wound healing. 


Laboratory studies and clinical trials have shown that honey is an effective broad-spectrum antibacterial agent. 


Honey antimicrobial action explains the external and internal uses of honey. Honey has been used to treat adult and neonatal postoperative infection, burns, necrotizing fasciitis, infected and nonhealing wounds and ulcers, boils, pilonidal sinus, venous ulcers, and diabetic foot ulcers. These effects are ascribed to honey's antibacterial action, which is due to acidity, hydrogen peroxide content, osmotic effect, nutritional and antioxidants content, stimulation of immunity, and to unidentified compounds. 


When ingested, honey also promotes healing and shows antibacterial action by decreasing prostaglandin levels, elevating nitric oxide levels, and exerting prebiotic effects. These factors play a major role in controlling inflammation and promoting microbial control and healing processes. This article reviews data supporting the effectiveness of natural honey in eradicating human pathogens and discusses the mechanism of actions.

Propolis Protects Against Gastric Ulcers due to Radiation Exposure

Propolis extract is very effective in treating mucous linings of the body...

Journal coverAnti-Ulcerogenic Effect of Aqueous Propolis Extract and the Influence of Radiation Exposure
International Journal of Radiation Biology, 2011 Jul 8

Purpose: to study the effect of aqueous propolis extract (AEP) against indomethacin (Indo)-induced gastric ulcers in irradiated and non-irradiated rats.

Materials and methods: animals were irradiated at different radiation dose levels before the induction of ulcers. AEP was injected orally one hour (h) before induction of gastric ulcers and the effects compared with those of lansoprazole (Lanso), which was used as a reference anti-ulcerogenic drug.

Results: pretreatment of rats, either irradiated or non-irradiated, with AEP effectively protected against Indo-induced gastric ulceration. This was associated with a reduction in acid output and peptic activity and an increase in the secretion of mucin. The mucosal prostaglandin E2 (PGE2) level was also increased. The levels of tumor necrosis factor-alpha (TNF-α) and interleukin-1beta (IL-1β) were suppressed to the same extent after treatment. Both propolis and Lanso were effective in reducing the number of gastric lesions as well as the plasma level of malondialdehyde (MDA).

Conclusions: These findings indicate that the gastroprotective effect of AEP could be of value in the management of excessive gastric damage induced by radiation exposure.
 
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