Apitherapy Symposium, Workshop Boston Area, April 28-29
Propolis Flavonoids Accelerate Wound Healing
Flavonoids in propolis acting on mast cell-mediated wound healing
Inflammapharmacology, 2012 Feb 17
Salvatore Chirumbolo, University of Verona Italy
![]() |
excerpt online at SpringerLink.com |
Honey Helps Treat Stomach Ulcers
Honey Wound Care Products Available for Veterinarians
Honey: The 'Bee Penicillin' That Could Even Beat MRSA
Horse Wounds Treated with Manuka Honey
Honey Effective in Management of Bed Sores
A Review of Honey and Microbial Infections
Honey has been used as a medicine throughout the ages and has recently been reintroduced to modern medical practice. Much of the research to date has addressed honey's antibacterial properties and its effects on wound healing.
Laboratory studies and clinical trials have shown that honey is an effective broad-spectrum antibacterial agent.
Honey antimicrobial action explains the external and internal uses of honey. Honey has been used to treat adult and neonatal postoperative infection, burns, necrotizing fasciitis, infected and nonhealing wounds and ulcers, boils, pilonidal sinus, venous ulcers, and diabetic foot ulcers. These effects are ascribed to honey's antibacterial action, which is due to acidity, hydrogen peroxide content, osmotic effect, nutritional and antioxidants content, stimulation of immunity, and to unidentified compounds.
When ingested, honey also promotes healing and shows antibacterial action by decreasing prostaglandin levels, elevating nitric oxide levels, and exerting prebiotic effects. These factors play a major role in controlling inflammation and promoting microbial control and healing processes. This article reviews data supporting the effectiveness of natural honey in eradicating human pathogens and discusses the mechanism of actions.
"I Can Heal Wounds with Honey and So Can You"
Next week, on July 25-29, management will show extreme cooperation in welcoming 20 beehives and 500 beekeepers for the annual meeting of the Eastern Apiculture Society. They will have talks on Colony Collapse Disorder, practical beekeeping including a bee yard, the business of keeping an apiary and treating illness with bee products and stings.
On Wednesday they will be regaled by Rhode Island’s own Charlie Hall and the Ocean State Follies, who will sting them all in a show they will not soon forget. If you have even a passing interest in bees, I recommend that you go to the Web site easternapiculture.org and sign up for a day or two.
I am presenting my literature review and work among the elderly in healing wounds with honey, based on 30 years of office practice and work as a medical director of Evergreen House Health Center, a nursing home in East Providence. I remember a comic TV routine with Mel Brooks interviewing Sid Caesar posing as a great Egyptologist. “So professor, what is the secret of Tutankhamen’s Tomb?” Quipped Caesar, “Twenty years of research and I should tell you?”
I am going to tell you. Speaking of Egyptian tombs, did you know that urns of honey were found undegraded in several tombs in ancient Egypt? This tells volumes about the amazing chemical nature of honey for wound-healing, to say nothing of the long association of the bees and humans.
How does honey help to heal wounds and why is it superior to neosporin, bacitracin and prescription mupirocin (bactroban)? Honey is bee spit but it is also their energy currency and their bank account. Just as “people get funny about their money” so, too, do bees get funny about their honey. They hate bears, bacteria and yeasts that may steal or spoil the honey. For the bears they have stingers, for the micro-organisms they put amazing stuff in the honey. They also seal the hive with an antimicrobial substance called propilis.
Honey is a mixture of concentrated sugars that immediately dehydrate a bacterial cell, rendering it immobile, though without necessarily killing it. Young Dr. Keith Monchik, of the Orthopedic Service at Rhode Island Hospital (RIH), went to Haiti with our team from the Ocean State to treat earthquake victims. They ran out of usual wound-care creams quickly but a senior military nurse reminded the team that sugar packs from their rations always work in a pinch to keep a wound from getting infected through the same mechanism. He reported gratifying results to the RIH medical staff.
The high osmotic value of honey draws fluids out of wounds. This decreases tissue pressure, thus admitting more new blood, with, of course, oxygen, as well as healing elements and protective immune-system cells. As the fluid hits the honey, small amounts of hydrogen peroxide are produced, very toxic to bacteria but not to fibroblasts and healing elements. Honey derived from medicinally active nectars such as tea tree and eucalyptus may have additional value, and the Food and Drug Administration has allowed their importation and marketing.
Topical antibiotic creams and ointments — both over the counter and prescription — are commonly used for skin infections and wound healing. These include neosporin, bacitracin, “triple-antibiotic” ointments and mupirocin. They sterilize the wound but also kill healing elements, leading to delayed wound closure. And they often lead to confusing red hypersensitivity reactions.
Additionally, more and more bacteria are growing resistant to antibiotics, which is a terrific threat to all of us. Some are costly. We should avoid these like the plague. My wife, Jane Dennison, M.D., is a pediatrician and beekeeper. As our house experienced colony collapse with drone migration of our four boys to New York City and Washington, my wife had the time to take the Bee Course offered by Rhode Island Beekeepers Association (RIBA) and start some hives. At the monthly RIBA meetings I spoke with the older beekeepers and was fascinated to learn of honey’s medicinal benefits. Some of the older beekeepers suggested that I try using honey mixed with Aquaphor ointment on my patients with minor wounds and ulcers. Honey at body temperature gets runny and dribbles on clothes, leading to poor treatment adherence. Aquaphor was already my favorite healing ointment. It is well-suited to mixing in equal parts with honey because the lanolin and mineral oil holds both aqueous and oily parts together to treat a wound.
Mixing large batches with the help of my mother in law, Jane Mackenzie, R.N., is sticky business indeed. She helps me pot it into little cosmetic jars for use in the nursing home. We heat the aquaphor to 110 degrees in the microwave but never put raw honey in the microwave because it would ruin its special qualities. And I urge you all: “Do this at home!.” You can’t buy it already made up.
If I were to try to sell this as a medicament, the Food and Drug Administration could have me jailed and impound all my ointment, because adequate studies on the effectiveness and safety of this compound have not been done. However, two imported products, Medihoney and Manuka Honey, have passed FDA approval for wound-healing. They are derived from the eucalyptus and tea tree plant, respectively, whose nectars have supposedly superior qualities. These honeys are irriadiated to inactivate trace amounts of botulinum toxin and bacteria.
I believe that raw honey needs no such help and that such help might even be counter-productive. This treatment and the importation increases the cost of treatment, with small tubes going for $50 to $100. I insist on the real thing when treating serious or stubborn wounds but for everyday use the product from your home lab will work very well on your cuts, burns and skin tears.
If you have diabetes and/or congestive heart failure peripheral arterial-supply problems, no ointment is going to help. The problem is under the skin. You need a doctor for it. I invite colleagues and hospitals to begin randomized controlled trials on using local raw honey head to head against imported honey and the usual wound-care products. My hypothesis is that we can control, at low cost, such superbugs as methacillin-resistant staphyllococus aureus and vancomycin-resistant enterococcous and the emergence of further resistant superbugs by avoiding the usual antibiotics.
Meanwhile, we’d be encouraging the development of new local hives, which are so important to pollination — and thus plant life and the broader eco-system — nationally. You may be interested in using bee stings to treat disease and honey to desensitize yourself to allergies. On July 28 the Apitherapy Association will make a presentation. You can find out information on the schedule and admission at easternapiculture.org.
Allen Dennison, M.D., is an assistant beekeeper and internist practicing in Barrington and East Providence.
Malaysian Tualang Honey Heals Wounds Faster Than Other Treatments
Indian J Plast Surg, 2011 Jan;44(1):112-7.
AIM: The effect of Tualang honey on wound healing in bacterial contaminated full-thickness burn wounds was evaluated in 36 male Sprague Dawley rats.
MATERIALS AND METHODS: The rats were randomly divided into three groups (n = 12/group). Three full-thickness burn wounds were created on each rat. Each group of rats was inoculated with a different organism in the burn wounds: Group A was inoculated with Pseudomonas aeruginosa, Group B was inoculated with Klebsiella pneumoniae and Group C was inoculated with Acinetobacter baumannii. One wound on each rat was dressed with either Tualang honey, Chitosan gel or Hydrofibre silver. Each wound size was measured on day 3, 6, 9, 12, 15, 18 and 21 of the study.
RESULTS: The mean wound size of the Tualang honey-treated wounds was not statistically different than that of the Chitosan gel or Hydrofibre silver-treated wounds when the wounds were compared throughout the entire experiment (P > 0.05). However, comparing the mean wound size on day 21 alone revealed that the Tualang honey-treated wounds were smaller in comparison to that of the Chitosan gel and Hydrofibre silver-treated groups.
CONCLUSIONS: This study shows that topical application of Tualang honey on burn wounds contaminated with P. aeruginosa and A. baumannii gave the fastest rate of healing compared with other treatments.
Clinical Evaluation in Lower Limb Wound Healing under Honey
Abstract
Introduction
Wound healing involves complex and multifactorial biological processes with overlapping stages [1]. However, in nonhealing wounds, successive repairing stages are affected by varied pathological happening including infection [2–4], imbalance in extracellular matrix formation and degradation [5, 6], impaired re-epithelialization [7] and nutritional supply, adverse microenvironment, and repeated physical trauma [8]. So, healing interventions need to address these pathological variables to facilitate cellular and molecular events towards re-epithelialization, connective tissue formation, and maturation of regenerating tissues [9–11]....Honey a Natural Support for Wound Healing

Perhaps most widely used as a natural culinary sweetener, honey also has many traditional uses as a health support, including its ability to coat sore throats, as an energizing pick me up, and as a soothing digestive aid.
How many of us think to use it on our wounds, though? You may want to add it to your medicine cabinet as a natural, cost effective support for wound healing!
Research suggests the natural acidity of unprocessed honey may be low enough to help prevent bacterial growth. In addition, honey absorbs water, which drys out the moisture bacteria rely on. Further studies suggest it may be an especially effective support for burns.
References
[1] Al-Waili NS.(2003). Topical application of natural honey, beeswax and olive oil mixture for atopic dermatitis or psoriasis: partially controlled, single-blinded study. Complement Ther Med. 11(4):226-34. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/15022655
[2] Eischen, N. (February/March 1999). The Benefits of Honey: A Remedy for Sore Throats, Wound Care and More. Mother Earth News. [Online] Retrieved from http://www.motherearthnews.com/Natural-Health/1999-02-01/Honey-Benefits.aspx
[3] Nasir, et al. (2010). Antibacterial properties of tualang honey and its effect in burn wound management: a comparative study. BMC Complement Altern Med. 10: 31. Published online 2010 June 24. doi: 10.1186/1472-6882-10-31. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908556/?tool=pubmed
[4] Waikato Honey Research Unit. (2009, September 3). What's special about Active Manuka Honey? The University of Waikato. Retrieved from http://bio.waikato.ac.nz/honey/special.shtml
This information is for educational purposes only. It is not intended to treat, diagnose, cure, or prevent disease. In an emergency, one should always call 911 or visit their primary care physician immediately.
Plant Yarrow in your garden, Today

Yarrow or botanically known as Achillea millefolium is one of the most precious herbs you can have in your garden.
A few years ago, my good friend and colleague Garth Kent told me about the use of Yarrow on bleeding wounds. Well I heard it ant it sort of sank into the sea of information. Last year Linnie started a vegetable garden at home and being the health nuts we are, we wanted to do it 100% natural and organic. This meant, for one, that we did not want to spray any chemical pesticides or herbicides. Linnie did a lot of research on organic gardening and decided to make use of companion planting.
Yarrow is considered an especially useful companion plant, not only repelling some bad insects while attracting good, predatory ones, but also improving soil quality. It attracts predatory wasps, which drink the nectar and then use insect pests as food for their larvae. Similarly, it attracts ladybugs and hoverflies. Its leaves are thought to be good fertilizer, and a beneficial additive for compost.
It is also considered directly beneficial to other plants, improving the health of sick plants when grown near them.
When she told me about Yarrow, I immediately remembered what Garth had told me, years earlier. Well, we planted some and it’s growing all over the veg garden. Some time ago, Danika cut her little finger badly, trying to cut an apple into slices. I was at work and Linnie was at home with the children. When an incident like this happens, my children are trained well. The nearest one will run to see what the matter is, if it’s more than they can handle, the will make alarm and we will get involved. One will run for our natural first aid kit,while the others will stand by for further instructions. In this particular instance, Linnie remembered about the fact that Yarrow stopped bleeding instantly. We had never used it but she decided to give it a try. So while she cleaned the wound, gushing with blood, with some Silvermax, Heidi-Mari ran to the garden and ripped off a piece of Yarrow leaf. Linnie bruised the leaf in the pestle and mortar and applied it to the wound.
Immediately the blood stopped, and the pain was gone instantly! The wound was healed by the next evening.
Now that was our first experience with Yarrow.
About a week ago, another alarm went off. This time it was David. The two boys were already in their bed, supposedly asleep, when we heard the blood curdling cry. I assumed that the one had hit the other one over a toy or something. I was making my way over there to go sort it out, when Josua came running in, shouting: “Come quickly dad, it’s David and there is blood everywhere!”
Now, if that did not get your adrenaline pumping then seeing the blood would. It was blood down his neck, his arm, on the stairs, on the bed - well, like Josua said, everywhere!
We assed the matter quickly, while shouting a few commands like Rescue!, Injura!, towel!and amongst them Yarrow! The older children ran to fetch what we requested. In the meantime I had put my hanky over the wound on the back of his head, but within seconds it was drenched in blood. I found a pile of serviettes, put them on, but the same happened. What seemingly had happened was that they played and David slipped and fell with the back of his head on the corner of a step.
It was then that I personally experienced the miracle of Yarrow. One of the older ones handed me a few leafs of Yarrow. I put it on the wound, and the bleeding stopped as if someone had turned off the tap!
I was amazed. We treated him for shock with more Rescue drops, and Injura drops. We put a little Traumeel S ointment on for the swelling, but the bleeding had stopped. For safety and to keep watch over him, we had him sleep near us for the night. What was furthermore amazing, was that David never once complained of any pain! The next day, he was his old self again.
So, I would seriously urge you, get Yarrow, and plant it in your garden, immediately.
Some other uses for Yarrow include the following.
Healing a Broken bone

When CJ got to me, his face filled with pain, I had realised he had received a hard blow from the naughty horse.
He got one kick on the fibula (between the knee and the ankle) and one on the foot's small bones (between the ankle and the little toe!!) His riding boot was kicked to pieces, and he could hardly walk.
A few weeks before, I had made him a small first aid kit that he could carry in his bag to the horses. In the past I just sent some Rescue and Injura drops, a few plasters and some Traumeel S ointment with him, which proved very useful over time, as he helped many children that came off a horse and met the ground with a rather sudden stop.
We immediately gave him some Rescue drops, followed by Injura drops. I carefully took the boot and sock off and discovered that (fortunately) it was not an open wound. I applied some Traumeel S ointment to the areas that was not well defined at this stage, as the pain was all over.



I then applied the wet part of the bandage to the foot and the fibula area.
We wrapped the bandage firmly around the area, and the pain disappeared within 5 minutes. I kept in doing this for about 4 days, at which point he was able to walk and jump again without any problems.

At the same time, during the days of his foot and leg healing I also fed him extra doses of the following supplements; CMO Capsules, Omega SLO capsules, Beriola capsules, Activ 8 antioxidants and extra Vitamin C capsules. I had him drink lots of filtered water with Coral Calcium sachets in the water. This makes the water highly alkaline and the Coral speeds up the healing tremendously.
