Apitherapy Symposium, Workshop Boston Area, April 28-29

These workshops and symposiums are fantastic, intense sessions on the truly marvelous merits of honeybees, helping humans and animals with better health...

The American Apitherapy Society, Inc. & the York County Beekeepers Association Present “Honey Bees for Health,” An Apitherapy Symposium & Workshop

April 28-29, 2012

York Harbor Inn, York Harbor, ME

For more information:

http://www.apitherapy.org

http://mainebeekeepers.org/news/honey-bees-for-health-an-apitherapy-symposium-workshop/

All are welcome to this event in York Harbor in Southern Maine, just one hour north of Boston, MA. You will be able to learn from three experienced Apitherapists (two physicians and one acupuncturist), and interact with them and other people interested in Apitherapy. 

This ancient form of medicine with products of the beehive (honey, pollen, propolis, bee venom, and royal jelly) is used for health and healing throughout the world. The use of these products to maintain health is currently becoming well recognized in mainstream as well as scientific publications, and their power to heal when illness or accident occurs is also documented.

Conditions such as arthritis, MS, pain, and wounds are known to respond well to Apitherapy. Examples of material covered at this event are:  

 - adverse reactions, 

 - informed consent 

 - legal issues,

 - treatment of scars

 - Veterinary Apitherapy

 - Apitherapy for pain, arthritis, and accidents

The AAS is a nonprofit membership organization established for the purpose of educating about Apitherapy. This event is a prelude to the more comprehensive program of AAS’s course and conference (known as CMACC) to be given this year, October 5 - 7 in Portland, Oregon.

AAS and YCBA look forward to having you with us at the end of April. Enjoy early Spring in Maine at a beautiful historic inn, close to many of southern Maine’s coastal natural resources, as well as to fine shopping.

Denver Bee Hosts Apitherapy Seminar, March 27

A special meeting with experienced apitherapist, Dr. Frederique Keller, is certified to be an enlightening, inspiring and stimulating event...  

Apitherapy Evening
March 27, 7pm

Location:  Denver Beekeepers Association Meting

Denver Police Station District 1 Community Room

1311 West 46th Avenue

Denver, Colorado 

Dr. Frederique Keller, licensed acupuncturist and medical herbalist in a private practice that also incorporates classical homeopathy and bee venom therapy as well as utilizes honey, pollen, propolis, royal jelly and bee bread where applicable. She also works in a second office specializing in sports and spinal injuries. 

1st ApiMedical Tourism Conf & ApiExpo, Bangladesh 22-24 June

Apitherapy is recognized complementary and alternative medicine in numerous countries around the world and is continuing to integrate into other countries' health care choices...

First International Api-Medical Tourism Conference, Api-Expo in Bangladesh

Bangladesh Tourism Foundation announced its 'First International Api-Medical Tourism Conference and Api-Expo' 2012 to be held at Dhaka Bangladesh from 22-24 June, 2012.

The Conference and Expo is open to apitherapists, beekeepers, tour operators, scientists and clinicians on beehive products with the objective of opening the world of apitherapy to medical people, beekeepers, alternative health practitioners and tour operators. The goal is that ApiMedical Tourism will rise due to the increasing interest in apiculture and apitherapy.

Speakers will deliver the keynotes in the plenary sessions that will improve and refresh the global knowledge base. The conference platform is targeted to health specialists, researchers and ordinary practitioners with a therapeutic interest towards the uses of honey, apitoxin, royal jelly, bees wax, propolis and bee pollen.

For more information, contact: 

Mokhlesur Rahman

President,

Bangladesh Tourism Foundation and Coordinator

First International Api-Medical Tourism Conference and Api-Expo 2012

Conference Secretariat

Room 305, Academic Building, Faculty of Business Studies, University of Dhaka, Bangladesh

Tel: (+8802)9661920-70 (hunting), Ext- 7970

Mobile: +880155245657, 01714117801

e-mail: gtldhaka@yahoo.com

Diabetic Foot Ulcers Healed With Royal Jelly

With over 185 organic compounds identified in Royal Jelly, is it any wonder that it possesses the same wound healing capacity as honey...

The Efficacy of Topical Royal Jelly on Diabetic Foot Ulcers Healing: A Case Series

J Res Medical Sciences, 2011 July

BACKGROUND:

Foot ulcers and infections are the major sources of morbidity in individuals with diabetes mellitus. This study aimed to evaluate the efficacy of topical Royal Jelly (a worker honey bee product) on healing diabetic foot ulcers.

METHODS:

Diabetic patients with foot ulcers that were referred to our clinic at Khorshid Hospital, Isfahan, Iran; were evaluated three times a week and treated according to standard treatments consisted of offloading, infection control, vascular improvement and debridement if required. In addition, all ulcers were measured and then topical sterile 5% Royal Jelly was applied on the total surface area of the wounds. Eventually, they were covered with sterile dressings. Each patient was followed for a period of three months or until the complete healing.

RESULTS:

A total of eight patients were enrolled in this study. Of these, two had two ulcers and, therefore, ten ulcers were evaluated. Two ulcers were excluded. Seven of the remained eight ulcers healed. Mean duration of complete healing was 41 days. One ulcer did not completely heal but improved to 40% smaller in length, 32% in width and 28% in depth. The mean length, width and depth reduction rates were 0.35 mm/day, 0.28 mm/day and 0.11 mm/day, respectively.

CONCLUSIONS:

Royal Jelly dressing may be an effective method for treating diabetic foot ulcers besides standard treatments.

Researchers Identify 185 Organic Compounds in Royal Jelly

The super-tonic effects of royal jelly are identified chromatically, along with their physiological benefits as a bactericide, a source of free amino acids and storage requirements for fresh royal jelly...

Gas Chromatographic-Mass Spectrometric Investigation of Volatile and Extractable Compounds of Crude Royal Jelly

J ChromatogrB Analyt Technol Biomed Life Sci, 2011 Dec 30

Using headspace solid-phase microextraction (HS-SPME) followed by diethyl ether and methanol extraction, it was possible to isolate as many as 185 organic compounds out of 17 samples of crude royal jelly (RJ). Of the above compound number, 169 compounds were positively identified by means of gas chromatography-mass spectrometry.

The volatile fraction of RJ consists of 25 different compounds where approximately 47% of the total ion current (TIC) of volatile compound chromatograms were composed of substances characterized by bactericidal (phenols) and repelling (octanoic acid and 2-heptanone) activities. Preliminary investigations have shown that RJ stored for 10 months at -18°C and 4°C keeps its composition of volatile compounds unchanged, however, at the same time at room temperature RJ phenol contents is decreased twice, whereas the fraction of aliphatic acids is increased 2.8 times due to the presence of both acetic and butyric acids.

The chromatogram of RJ ether extracts showed 85 different compounds, however about 88% of TIC consisted exclusively of 8 compounds, i.e. 10-hydroxy-2-decenoic, 10-hydroxydecanoic, 3,10-dihydroxydecanoic, 8-hydroxyoctanoic, 2-decene-1,10-dioc and (Z)-9-hydroxy-2-decenoic acids. Nine aliphatic acids, which were detected for the first time, are the homologues of hydroxy- and oxo-acids identified earlier in RJ. In the RJ methanol extracts 82 compounds were identified, mainly carbohydrates and their derivatives.

Approximately 87% of TIC consisted of fructose, glucose and sucrose. Special attention was paid to discrepancies between obtained and literature data concerning the presence of free amino acids in RJ. It was suggested that these inconsistencies can be explained by the differences in the methods of RJ collection and/or sample preparation.

Conclusion:

► Volatile compounds of fresh royal jelly. 

► Bactericidal and repelling activities. 

► Markers of inappropriate storage. 

► Extractable compounds of royal jelly. 

► Possible source of free amino acids.

Apithérapie: Médecine d'Avenir, Thérapie de toujours et d'aujourd’hui

Conférence en France sur l'Apitherapie qui va montrer comment on peux vivre mieux avec les produits des abeilles...
French Apitherapy conference showing how we can live better with products from the beehive...

Samedi 21 et dimanche 22 janvier 2012 à Lille             
Premier Colloque International Francophone d’Apithérapie
plus d'infos: afacontact@gmail.com

SAMEDI 21 JANVIER 2012

9h à 9h30 Ouverture du colloque et présentation de la revue d’apithérapie par l’AFA et l’UNAF

Dr Albert BECKER, Docteur en médecine générale, président de l’AFA, président du CETAM (Centre Technique Apicole de Moselle)

9h30 à 10h L’homme et l’abeille

Henri CLÉMENT, apiculteur professionnel, porte parole de l’UNAF

10h à 10h30 La grippe, intérêt de la propolis par son action anti-virale

Nicolas CARDINAULT, Docteur en nutrition, Directeur de Recherches

11h à 11h30 Plaie : Cicatrisation par le miel

Dr Albert BECKER, Docteur en médecine générale, président de l’AFA, président du CETAM

11h30 à 12h Présentation des effets attendus des pro-biotiques de la ruche, entre autre rectocolite hémorragique et maladie de Crohn

Patrice PERCIE DU SERT, ingénieur en agriculture, apiculteur et président d'une entreprise de fabrication de produits de la ruche

14h à 15h30 Les abeilles aux services de la santé de l’Homme, une belle économie pour la santé

Professeur Henri JOYEUX, Professeur de cancérologie et chirurgie digestive à la Faculté de médecine de Montpellier

15h30 à 16h Les différentes méthodes pour l'analyse de la qualité de la propolis (sublimation, HPLC, colorimétrie, etc.)

Alain BEKAERT, Pharmacien et Maître de Conférence à la Faculté de pharmacie de Paris

16h30 à 17h L’action anti-cancéreuse directe et indirecte de la propolis

Nicolas CARDINAULT, Docteur en nutrition, Directeur de Recherches

17h à 17h30 Les différentes méthodes de récolte de la propolis

Patrice PERCIE DU SERT

17h30 à 19h Une table sur « la médecine par les abeilles, l’apithérapie en question »

DIMANCHE 22 JANVIER 2012

9h à 9h30 Quel avenir pour l’apiculture ?

Henri CLEMENT, apiculteur professionnel, porte parole de l’UNAF

9h30 à 10h Prévention et traitement des intolérances/allergies/choc anaphylactique au venin d'abeilles

Dr Stéfan STANGACIU

10h à 10h30 Gelée royale de qualité et thérapie

Professeur Eberhart BENGSCH, Docteur en Sciences, biochimie, virologie, apidologie, Institut Max Planck, Munich (Allemagne) ; Vice-président de l’AFA, expert mondialement reconnu concernant la gelée royale et ses effets antiviraux.

11h à 11h30 Le venin d'abeille médicament : le paradoxe d'un poison qui soigne 

Dr Claude NONOTTE-VARLY, Allergologue, Médecin libérale et attaché des hôpitaux de Hyères et à Ste Anne de Toulon

11h30 à 12h Analyse biologique et chimique des produits de la ruche (application médicale) expérience du CETAM

Dr Albert BECKER

14h à 17h L’apithérapie dans le monde aujourd’hui ouvert au grand public - Accès gratuit

Dr Albert BECKER, Patrice PERCIE DU SERT, Henri CLÉMENT

15 à 17h Ateliers pratiques : Massage au miel, Api-Cosmétique, Digitoponcture, Réflexothérapie avec crèmes à bases de produits d'abeilles, Préparation des produits d'abeilles

14h à 15h30 Les abeilles aux services de la santé de l’Homme, une belle économie pour la santé

Professeur Henri JOYEUX, Professeur de cancérologie et chirurgie digestive à la Faculté de médecine de Montpellier

15h30 à 16h Les différentes méthodes pour l'analyse de la qualité de la propolis (sublimation, HPLC, colorimétrie, etc.)

Alain BEKAERT, Pharmacien et Maître de Conférence à la Faculté de pharmacie de Paris

16h30 à 17h L’action anti-cancéreuse directe et indirecte de la propolis

Nicolas CARDINAULT, Docteur en nutrition, Directeur de Recherches

17h à 17h30 Les différentes méthodes de récolte de la propolis

Patrice PERCIE DU SERT

17h30 à 19h Une table sur « la médecine par les abeilles, l’apithérapie en question »

pdf de prog

Royal Jelly Anti-Tumor Effect Studied

Royal Jelly posseses very important components. One in particular, the amazing 10H2DA, is currently being studied to stop cancer cells from growing, modulate Estrogen and treat Rheumatoid Arthritis (RA). The natural wonders of the beehive, known as Apitherapy, have real therapeutic value.

Inhibition of Interferon-γ-Induced Nitric Oxide Production by 10-Hydroxy-Trans-2-Decenoic Acid Through Inhibition of Interferon Regulatory Factor-8 Induction

Cellular Immunology, 2011 Dec

10-Hydroxy-trans-2-decenoic acid (10H2DA) is a major lipid component of royal jelly, a honey bee secretion used to nourish the queen bee and young larvae.

In this study, we examined the effect of 10H2DA on interferon (IFN)-γ-induced nitric oxide (NO) production. IFN-γ-induced NO production and activation of the inducible NO synthase promoter were significantly inhibited by 10H2DA. IFN-γ-induced phosphorylation of signal transducer and activator of transcription-1 was not affected by 10H2DA. In contrast, IFN-γ-induced tumor necrosis factor (TNF)-α production and nuclear factor (NF)-κB activation were inhibited by 10H2DA. IFN-γ-mediated induction of interferon regulatory factor (IRF)-8, but not IRF-1, was also inhibited by 10H2DA. IFN-γ-induced TNF-α production followed by activation of NF-κB is known to be essential for NO production.

Together, 10H2DA inhibited IFN-γ-induced NO production by inhibiting IRF-8 induction and TNF-α production. 10H2DA might modulate IFN-γ-mediated cellular responses by inhibiting the induction of IRF-8 and IRF-8-dependent genes.

Royal Jelly May Help Treat Menopausal Syndrome

Hormonal influences from Royal Jelly are consistently showing up in studies with women and men. And it's frequently found to provide regulatory action -- auto-pilot to the rescue with an apiphytotherapy blend. 

Effectiveness of a Herbal Formula in Women with Menopausal Syndrome

ForschKomplementmed (Research in Comp Med) 2011, Oct 

Background: 

Lady 4 is a combination of 4 natural components (evening primrose oil, damiana, ginseng, royal jelly) with a known history of traditional use for menopausal symptoms.

Objective:

To study efficacy and safety of Lady 4 in women suffering from menopausal syndrome.

Methods:

120 women with menopausal symptoms were randomised into an experimental group treated with 2 capsules of Lady 4 daily and a control group treated with placebo. The outcome was measured by the Menopause Rating Scale II (MRS-II).

Results:

There was a statistically significant improvement in the MRS-II score in both groups after 2 and 4 weeks of treatment, but the improvement was significantly better in the Lady 4 group. 86.7% in the Lady 4 group and 56.7% in the placebo group rated the therapy success as 'much improved' or 'very much improved'.

Conclusion: 

Lady 4 may be beneficial in the treatment of menopausal syndrome and can be used as a safe natural promoter of health and well-being in women during the menopausal transition.

Royal Jelly Possesses Skin-Whitening, Therapeutic Properties

perhaps a correlation between the naturally, occuring Pantothenic Acid in Royal Jelly and its affect on skin cell development...

Royal Jelly Reduces Melanin Synthesis Through Down-Regulation of Tyrosinase Expression

Am J ChinMed, 2011, Vol. 39, Issue 6

For cosmetic reasons, the demand for effective and safe skin-whitening agents is high. Since the key enzyme in the melanin synthetic pathway is tyrosinase, many depigmenting agents in the treatment of hyperpigmentation act as tyrosinase inhibitors.

In this study, we have investigated the hypo-pigmentary mechanism of royal jelly in a mouse melanocyte cell line, B16F1. Treatment of B16F1 cells with royal jelly markedly inhibited melanin biosynthesis in a dose-dependent manner. Decreased melanin content occurred through the decrease of tyrosinase activity. The mRNA levels of tyrosinase were also reduced by royal jelly.

These results suggest that royal jelly reduces melanin synthesis by down-regulation of tyrosinase mRNA transcription and serves as a new candidate in the design of new skin-whitening or therapeutic agents...

Royal Jelly Beneficial for Hypertension, Cholesterol, Bone Loss & Male Infertility

Royal Jelly continues its climb upwards as a respected product for treating important human conditions...

Clinical Advisor, 4-Oct 2011

 …Royaljelly contains a complex mixture of proteins, vitamins, minerals andcarbohydrates. The B vitamins are found in the largest quantity, followedclosely by an assortment of 20 different amino acids, calcium, zinc, iron andmanganese.

A detailedbreakdown of the constituents of royal jelly reveals lipids (3%-7%),carbohydrates (10%-12%), proteins (12%-15%), water (60%-70%) and traces ofminerals and vitamins. Of particular medical interest is the presence of gammaglobulin, one of a group of specific proteins studied for theirimmune-modulating potential and pro-estrogenic compounds...

Science


Due to itsrich content of antioxidants, proteins and other nutrients, royal jelly isreportedly good for whatever ails you. It is specifically recommended fortreatment of hypertension, hyperlipidemia and inflammation, and is beingstudied for a possible anti-tumor effect as well as a treatment for maleinfertility.

In a smalltrial, patients were assigned to the royal jelly intervention or placebo. Treatment-groupparticipants were given 6 g daily of royal jelly formulation for four weeks. Atthe end of the trial, the treatment group's total cholesterol level was reduced6%, and LDL was reduced more than 9%.

Egyptianresearchers investigated the effect of royal jelly on conception rates amongcouples with known male asthenozoospermia... At the end of three monitoredcycles, the successful conception rate of the treatment group was 8.1% comparedwith only 2.6% of the IUI couples. The researchers are still studying themechanism of action in this usage beyond the nutrition-dense composition ofroyal jelly. 


The growthand development of bone cells is another area of focus for royal jellyresearch. Scientists monitored tibial bone density in ovariectomized rats forseven weeks until clinical measurements indicated significant loss of bonedensity. At this point, the treatment group was given a royal jelly supplementand the active control group was given a 17 beta-estradiol treatment.

At the endof treatment, the active control group had 100% reversal of tibial bone loss,and the royal jelly group showed 85% bone recovery. Enhanced gastric absorptionof calcium was found in this and other studies and could account for a synergisticeffect on bone maintenance.
..


Royal Jelly Improves Cognitive Function and Memory

a concise summary of numerous studies...  Is Royal Jelly the solution for other deficiencies?... 

ImproveCognitive Function and Memory with RoyalJelly

Apitherapyreview.org

By WilliamRudolph for Apitherapy Commission of Apimondia

Royal jellyis one of the most nutritionally complex foods on the planet with the abilityto shore up many nutritional deficiencies and may help people overcome conditionsthey may have been dealing with for years. Royal jelly is also highly regardedfor its brain-boosting capabilities. Whether you are a young student lookingfor an edge on an exam, a CEO with tremendous demands on your time, or havereceived the devastating diagnosis of Alzheimer`s disease, royal jelly may beable to deliver remarkable results.

Royal Jellyand the Acetylcholine Connection

Royal jellyis a creamy substance produced by the common worker bee; one of the purposes isof developing and nourishing the queen bee. On this diet of royal jelly, thequeen bee will typically grow to be 40 percent larger and can live up to 40times longer than the worker bee. Royal jelly isn`t just food for the queenbee, it`s her longevity strategy.

Royaljelly`s structure and composition has not, so far been replicated by man in anylab. The only lab capable of producing such a substance is the bee hive. Thissuperfood is rich in protein, loaded with B vitamins, and contains many otherminerals and nutrients. One of the key ingredients in royal jelly that may haveprofound implications for improving memory and invigorating mental acuity isacetylcholine.

Acetylcholinewas the first neurotransmitter discovered. It is found in the brain, spinalcord, and throughout areas of the nervous system. It regulates memory and isneeded to transmit nerve messages from cell to cell. Interestingly, royal jellyis the only natural source of pure acetylcholine. Optimal levels ofacetylcholine in the brain are associated with improved memory, fluidity ofthought, and enhanced cognitive function.

Implicationsfor Alzheimer`s Disease

Part of thewonderful symmetry of nature is its ability to deliver a formidable solutionequivalent to virtually any problem you encounter. Though conventional medicinehas not found a cure for Alzheimer`s disease, royal jelly may offer substantialbenefits. Alzheimer`s disease is a progressive, degenerative, neurologicaldisease that is thought to be irreversible. It usually afflicts people afterthe age of 65 and is the fourth leading cause of death among adults. Thepathology of Alzheimer`s disease includes the presence of extracellular plaques(clusters of dead and dying nerve cells) and intracellular"neurofibrillary tangles" (twisted fragments of protein within nervecells). These plaques and fibrous entanglements in the brain disrupt lines ofcommunication and inhibit the production of acetylcholine. This leads to loss ofmemory, anxiety, irritability, and difficulty in expressing thoughts.

Mosttraditional treatments pursued by Western medicine try to increase levels ofacetylcholine in the brain of the Alzheimer`s patient. These drugs attempt toraise the levels of acetylcholine by inhibiting the enzymes that lead to thebreakdown or degradation of acetylcholine. Royal jelly, however, can raiselevels of acetylcholine without the side effects often associated with the useof medications, such as nausea and liver toxicity.

Initiallywhen looking at royal jelly as a brain-boosting strategy, it may appear costprohibitive. Keep in mind that this gift from the hive is truly one of theelite superfoods available anywhere. It is also highly potent and concentrated,so a little goes a long way. It can be found in its traditional, jelly-likeform and ingested directly. Also, modern advances in formulation technologyhave made it available now in a freeze dried, powdered form that is perfect formixing with smoothies or adding to a homemade sports drink.

Resources:

http://en.wikipedia.org/wiki/Acetylcholine

http://psyweb.com/Documents/00000003.jsp

http://www.ncbi.nlm.nih.gov/pubmed/20298170

http://en.wikipedia.org/wiki/Alzheimer

http://www.herbs2000.com/h_menu/bp_royal_jelly.htm

http://thenaturalshopper.com/beeproducts/royaljelly.html

http://www.vitamins-supplements.org/nutrients/royal-jelly.php

WilliamRudolph is a natural health enthusiast who enjoys researching and learningabout natural health approaches and strategies, longevity techniques, andnatural ways of achieving peak performance

Royal Jelly Protects Kidneys, Liver from Anti-Cancer Treatments

New research from Turkish researchers confirm the protective properties of Royal Jelly against damage caused by anti-cancer therapies. Could this be new ground towards complementary alternative therapies? 

Royal Jelly Modulates Oxidative Stress and Apoptosisin Liver and Kidneys of Rats Treated with Cisplatin

Oxidative Medicine and Cell Longevity, Volume 2011(2011)

Abstract:

Cisplatin (CDDP) is one of the most active cytotoxicagents in the treatment of cancer and has adverse side effects such asnephrotoxicity and hepatotoxicity. The present study was designed to determinethe effects of royal jelly (RJ) against oxidative stress caused by CDDP injuryof the kidneys and liver, by measuring tissue biochemical and antioxidantparameters and investigating apoptosis immunohistochemically.

Twenty-four Sprague Dawley rats were divided into fourgroups, group C: control group received 0.9% saline; group CDDP: injected i.p.with cisplatin (CDDP, 7 mg kg(-1) body weight i.p., single dose); group RJ:treated for 15 consecutive days by gavage with RJ (300 mg/kg/day); group RJ +CDDP: treated by gavage with RJ 15 days following a single injection of CDDP.Malondialdehyde (MDA) and glutathione (GSH) levels, glutathione S-transferase(GST), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD)activities were determined in liver and kidney homogenates, and the liver andkidney were also histologically examined.

RJ elicited a significant protective effect towardsliver and kidney by decreasing the level of lipid peroxidation (MDA), elevatingthe level of GSH, and increasing the activities of GST, GSH-Px, and SOD. In theimmunohistochemical examinations were observed significantly enhanced apoptoticcell numbers and degenerative changes by cisplatin, but these histologicalchanges were lower in the liver and kidney tissues of RJ + CDDP group. Besides,treatment with RJ lead to an increase in antiapoptotic activity hepatocytes andtubular epithelium.

In conclusion, RJ may be used in combination withcisplatin in chemotherapy to improve cisplatin-induced oxidative stressparameters and apoptotic activity...

excerpt:

Recently, royal jelly (RJ) has received particularattention because of studies that have reported that it is a highly efficientantioxidant and has free radical scavenging capacity [4, 15]. Royal jelly is asecretion produced by the hypopharyngeal and mandibular glands of workerhoneybees (Apis mellifera). It contains many important compounds withbiological activity such as free amino acids, proteins, sugars, fatty acids,minerals, and vitamins [16]. So far, RJ has been demonstrated to possessseveral physiological activities in experimental animals, includingvasodilative and hypotensive activities [17], the induction of decrease inserum cholesterol levels [18], antimicrobial [19], antiallergic [20],anti-inflammatory [21], immunomodulatory [22, 23], and antioxidant properties[16]. In addition, Kanbur et al. [24] revealed the protective effect of RJagainst paracetamol-induced liver damage in mice.

AAS Apitherapy Course & Conf - New Orleans, Nov 4-6 2011

an intensive, learning experience designed to increase your knowledge and use of Apitherapy...

The American Apitherapy Society proudly announces its2011 Charles Mraz Apitherapy Course & Conference to be held in New Orleans, Louisiana Nov 4-6 2011.For the first time ever we are offering 2 course levels, one for those new toapitherapy and the other for those who are already familiar with or are alreadypracticing apitherapy.

Medical doctors, a spectrum of holistic healthpractitioners, veterinarians, researchers, backyard beekeepers, and members ofthe general public interested in self-reliant health care will convene from allover the United statesand the world to learn about apitherapy. Apitherapy, an ancient healing modality, refers to the therapeutic useof products from the beehive: honey, pollen, royal jelly, propolis, and beevenom therapy. 

Attendees will receive education on basic and moreadvanced levels on the products of the hive and their therapeutic propertiesincluding a hands on bee venom therapy workshop where participants can obtainpractical experience with this healing practice.  Presentations are given by the CMACC facultywho are some of the most prominent and experienced Apitherapists in thecountry.  Examples of material covered inthese presentations are allergic reactions, techniques of BVT, informed consentand legal issues, propolis and cancer, veterinary apitherapy, patient intakefor apitherapy, and much more.  An examis given to ascertain comprehension of the material in the course andcertificates of completion will be issued.

The AAS is a nonprofit membership organization establishedfor the purpose of education about apitherapy. CMACC has been named in memory of Charles Mraz, an American pioneer in theuse of bee venom to treat diseases.

Visit www.apitherapy.org where with a single click youcan access all CMACC information, register and pay online.  Don’t miss out on the EARLY BEE DISCOUNT bymaking sure you register by Friday, September 23rd. Do join us for the Fridaynight dinner to network with others and experience the New Orleans cuisine. Don’t forget to mentionAAS when booking your hotel room in order to receive a special rate valid untilOctober 6th. Membershipto AAS is included with  the course fee.

Contact:  American Apitherapy Society

631-470-9446  aasoffice@apitherapy.org 

2011 Charles Mraz Course and Conference (CMACC)

November 4-6, 2011

The Inn on Bourbon

541 Bourbon Street, New Orleans, LA  70130

1-800-535-7891 or 504-524-7611 

Royal Jelly Can Treat & Prevent Periodontal Diseases

See excerpt below: 'Royal Jelly prevents osteoporosis'... another medical discovery from the beehive...

Osteoinductive and Anti-Inflammatory Effect of Royal Jelly on Periodontal Ligament Cells

Biomed Res, 2011;32(4):285-91

Royal jelly (RJ) has been reported to possess several physiological and pharmacological properties such as the ability to prevent osteoporosis in rats and anti-inflammatory effects. We hypothesized that RJ could have beneficial effects on the prevention or treatment of periodontal diseases, which are chronic inflammatory diseases caused by bacterial infection that result in resorption of the tooth-supporting bone.

We assessed the effect of RJ on mineralization in mouse periodontal ligament cell clone 22 (MPDL22 cells), which are of an osteogenic and cementogenic lineage. The mRNA expression of osteopontin, osteocalcin and osterix, and mineralized nodule formation were significantly enhanced in RJ-treated MPDL22 cells.

In addition, we investigated the effects of RJ on the production of inflammatory cytokines from MPDL22 cells stimulated with lipopolysaccharide (LPS) of Porphyromonas gingivalis, a periodontopathic bacterium. RJ suppressed LPSinduced interleukin-6 and CXC chemokine ligand 10 production from MPDL22 cells. Furthermore, RJ suppressed the expression of CD54 in MPDL22 cells: CD54 is the adhesion molecule involved in the accumulation of leukocytes in periodontal lesions.

These findings suggest that the osteoinductive and anti-inflammatory effects of RJ can provide benefits for the treatment and prevention of periodontal diseases...

Royal Jelly Has Lifespan-Extending Effect

Reinforces what we know - the queen lives much longer due to her exclusive diet of Royal Jelly...

Lifespan-Extending Effects of Royal Jelly and Its Related Substances on the Nematode Caenorhabditis elegans
PLoS ONE 6(8): Published: August 9, 2011

Background

One of the most important challenges in the study of aging is to discover compounds with longevity-promoting activities and to unravel their underlying mechanisms. Royal jelly (RJ) has been reported to possess diverse beneficial properties. Furthermore, protease-treated RJ (pRJ) has additional pharmacological activities. Exactly how RJ and pRJ exert these effects and which of their components are responsible for these effects are largely unknown. The evolutionarily conserved mechanisms that control longevity have been indicated. The purpose of the present study was to determine whether RJ and its related substances exert a lifespan-extending function in the nematode Caenorhabditis elegans and to gain insights into the active agents in RJ and their mechanism of action.

Principal Findings

We found that both RJ and pRJ extended the lifespan of C. elegans. The lifespan-extending activity of pRJ was enhanced by Octadecyl-silica column chromatography (pRJ-Fraction 5). pRJ-Fr.5 increased the animals' lifespan in part by acting through the FOXO transcription factor DAF-16, the activation of which is known to promote longevity in C. elegans by reducing insulin/IGF-1 signaling (IIS). pRJ-Fr.5 reduced the expression of ins-9, one of the insulin-like peptide genes. Moreover, pRJ-Fr.5 and reduced IIS shared some common features in terms of their effects on gene expression, such as the up-regulation of dod-3 and the down-regulation of dod-19, dao-4 and fkb-4. 10-Hydroxy-2-decenoic acid (10-HDA), which was present at high concentrations in pRJ-Fr.5, increased lifespan independently of DAF-16 activity.

Conclusions/Significance

These results demonstrate that RJ and its related substances extend lifespan in C. elegans, suggesting that RJ may contain longevity-promoting factors. Further analysis and characterization of the lifespan-extending agents in RJ and pRJ may broaden our understanding of the gene network involved in longevity regulation in diverse species and may lead to the development of nutraceutical interventions in the aging process.

Royal Jelly May Help Treat Depression and Anxiety

This research confirms what has been noted before of Royal Jelly's overall positive tonic effect ...

Antidepressant-Like Activity of 10-hydroxy-trans-2-decenoic acid, a Unique Unsaturated Fatty Acid of Royal Jelly, in Stress-Inducible Depression-Like Mouse Model
Evid Based Complement Alternat Med, 2012;2012:139140. Epub 2011 Jul 24

Royal jelly (RJ), which is fed to the queen honeybee, has a variety of biological activities towards various types of cells. For instance, RJ exhibits immunomodulatory properties [1–3] and inhibits the development of atopic dermatitis-like skin lesions [4]....


Symptoms of depression and anxiety appeared in mice after they had been subjected to a combination of forced swimming for 15 min followed by being kept in cages that were sequentially subjected to leaning, drenching, and rotation within 1-2 days for a total of 3 weeks. 

The animals were then evaluated by the tail-suspension test, elevated plus-maze test, and open-field test at 1 day after the end of stress exposure. Using these experimental systems, we found that 10-hydroxy-trans-2-decenoic acid (HDEA), an unsaturated fatty acid unique to royal jelly (RJ), protected against the depression and anxiety when intraperitoneally administered once a day for 3 weeks simultaneously with the stress loading. Intraperitoneally administered RJ, a rich source of HDEA, was also protective against the depression, but RJ given by the oral route was less effective...


 These results demonstrate that HDEA and RJ, a natural source of it, are effective in ameliorating the stress-inducible symptoms of depression and anxiety and suggest that they may become a promising tool as a new antidepressant.

Royal Jelly Powder Acts as a Brain Food

It's not called royal for nothing... Royal Jelly is good for the brain and the body...

(NaturalNews, Sunday, July 24, 2011 by: Alex Malinsky aka RawGuru)

An interesting product, to say the least, royal jelly is the food that turns regular bee larvae into queen bees - it's the substance that elevates the physical capabilities of certain bees to allow them to become leaders of their own hives. Secreted by the nurse bees that look after the larvae in a hive, royal jelly causes some of the baby bees to grow faster and stronger than the rest. Claims have been made that when consumed by humans royal jelly can act as a "brain food," providing the boost the brain needs to grow faster and more efficient.

This claim is made because royal jelly contains a rare fatty acid, 10-HDA, that is said to enhance the cognitive capabilities of individuals. Due to a high concentration of phospholipids, people that consume royal jelly are able to improve their motor function, short-term memory, learning abilities, and overall awareness. Studies have shown that royal jelly has even been able to improve the conditions of individuals that suffer from Alzheimer's and Parkinson's diseases. The availability of a natural therapy for such illnesses is certainly important, as the market's current medications are laden with harsh chemicals that often provide serious side effects.

Despite the fact that royal jelly is recognized as a brain food, it remains that this natural remedy has much more to offer than increased brain function. As a substance that contains many B vitamins (especially Vitamin B5, pantothenic acid), trace minerals, and antibacterial proteins, royal jelly provides a natural boost of overall well-being. Some of its many other health benefits are:

* Efficient regeneration of tissue, especially that involving DNA.

* Increase in the strength of white blood cells, which boosts the immune system.

* Reduction of oxygen supplied to tumors, allowing the body to fight several types of cancer.

* Regulations of blood sugar, which can improve the health of individuals with diabetes.

* DHEA, a hormone that has anti-aging and adrenal-regulating properties.

* Restoration of the function of both the adrenal and kidney systems.

* Faster hair growth that also improves shine and color, due to para-aminobenzoic acid.

* Younger looking skin, a result of collagen and zinc.

* Rest and renewal after being overworked or excessively tired.

* Relief from asthenia, anxiety, insomnia, asthma, arthritis, gout, skin problems, and even broken bones.

* Lower cholesterol.

* Increased anti-inflammatory and antibiotic capabilities.

The use of royal jelly powder has been deemed safe for the majority of individuals; however, people that suffer from allergies or are allergic to royal jelly may suffer from an allergic reaction that could be fatal. Therefore, knowing all allergies before taking the supplement is crucial to achieving success when incorporating royal jelly into a diet.

Individuals who choose to add royal jelly powder can expect to experience an overall boost in their health. These many benefits will provide a well-rounded increase in well-being, allowing users to feel more alert and more comfortable. Though it is advertised as a "brain food," and does contain substances that can boost the activity of the brain and nervous system, royal jelly also provides many other highly valuable health benefits that make it an important supplement in the lives of people who are seeking natural remedies.